Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles G. Glabe, Austin Yang, Michela Gallagher, Karen H. Ashe

SUMMARY: Memory function often declines with age, and is believed to deteriorate initially because of changes in synaptic function rather than loss of neurons. Some individuals then go on to develop Alzhe

CONTEXT: ...{superIncludes}/super.body-top.fhtml") Memory function often declines with age, and is believed to deteriorate initially because of changes in synaptic function rather than...

Nature 440, 352-357 Letter

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Richard Morris, Lennart Mucke

SUMMARY: Abnormal protein clumps of many varieties build up in the brains of individuals with Alzheimer's disease. But which types actually cause memory deficits? The behaviour of model mice might help to

CONTEXT: ...disease-causing protein assemblies. In this issue, Karen Ashe and her colleagues (Lesne et al., page 352) describe the isolation of a specific protein assembly from mouse...

Nature 440, 284-285 News and Views

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